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L-tryptophan is an amino acid, a protein building block that can be found in many plant and animal proteins. L-tryptophan is called an “essential” amino acid because the body can't make it. It must be acquired from food.
L-tryptophan is used for insomnia, sleep apnea, depression, anxiety, facial pain, a severe form of premenstrual syndrome called premenstrual dysphoric disorder (PMDD), smoking cessation, grinding teeth during sleep (bruxism), attention deficit-hyperactivity disorder (ADHD), Tourette's syndrome, and to improve athletic performance.
How does it work?
L-tryptophan is naturally found in animal and plant proteins. L-tryptophan is considered an essential amino acid because our bodies can't make it. It is important for the development and functioning of many organs in the body. After absorbing L-tryptophan from food, our bodies convert it to 5HTP (5-hyrdoxytryptophan), and then to serotonin. Serotonin is a hormone that transmits signals between nerve cells. It also causes blood vessels to narrow. Changes in the level of serotonin in the brain can alter mood.
Possibly Effective for...
- Treating premenstrual dysphoric disorder (PMDD). Taking 6 grams of L-tryptophan per day seems to decrease mood swings, tension, and irritability in women with PMDD.
- Smoking cessation (helping people quit smoking). Taking L-tryptophan seems to improve the effectiveness of conventional treatment for smoking cessation.
Possibly Ineffective for...
- Treating teeth grinding (bruxism).
- Treating facial pain.
- Improving athletic ability.
- Depression. Developing research suggests that L-tryptophan might improve the effectiveness of common medications for depression.
- Seasonal affective disorder (SAD). Early research suggests L-tryptophan might be helpful in SAD.
- Attention deficit-hyperactivity disorder (ADHD). There is some evidence that L-tryptophan levels are lower in children with ADHD; however, taking L-tryptophan supplements does not appear to improve ADHD symptoms.