Nicotinamide Riboside 400mg Capsules 

NR Boost NAD Supplement 

✅CERTIFIED 99.%PURE ✅ CLEAN-NO FILLERS✅ BOOST NAD+

Made in House at Charge Products - UK's Leading Supplier of NAD Supplements. Wholesale Welcome

Nicotinamide riboside (NR) is a form of vitamin B3 (niacin) that has gained attention for its potential health benefits, primarily due to its role in increasing levels of NAD+ (nicotinamide adenine dinucleotide), a coenzyme involved in energy production and various cellular processes. Here are some of the potential health benefits of nicotinamide riboside:

1. Improved Cellular Energy Production

NAD+ is crucial for converting food into energy. As we age, NAD+ levels decline, which can impact cellular function. NR supplementation can boost NAD+ levels, potentially enhancing cellular energy production and overall vitality.

2. Support for Healthy Aging

Increased NAD+ levels are thought to support the activity of sirtuins, a group of proteins associated with longevity and cellular repair. Some animal studies suggest that boosting NAD+ may help slow age-related decline in muscle and organ function.

3. Enhanced Metabolism and Fat Loss

Some studies have indicated that NR may support healthy metabolism by increasing energy expenditure and fat oxidation. This could potentially help with weight management and reduce the risk of obesity-related diseases.

4. Improved Muscle Function

By increasing NAD+ levels, NR may help improve muscle function, especially in older adults. Research shows that NAD+ plays a role in muscle repair and regeneration, which can support physical performance and recovery.

5. Neuroprotective Effects

There’s evidence suggesting that NR could protect brain cells from damage and improve cognitive function. NAD+ is essential for maintaining brain health, and increased NAD+ might help defend against neurodegenerative Brain Health such as Alzheimer's or Parkinson's, though more research is needed.

6. Heart Health

Some studies have shown that NR may benefit cardiovascular health by improving blood vessel function, reducing inflammation, and promoting healthy blood pressure. The increase in NAD+ could help protect the heart and improve blood circulation.

7. Anti-Inflammatory Effects

NR has been shown to have anti-inflammatory properties, which can be beneficial in managing chronic inflammation ,

8. Potential for DNA Repair

NAD+ is also involved in DNA repair. With age, DNA damage accumulates, and increasing NAD+ levels may help repair some of that damage.

9. Improved Insulin Sensitivity

Some research has shown that NR may improve insulin sensitivity, which could be beneficial in reducing the risk of type 2 diabetes. By enhancing NAD+ levels, NR could help improve glucose metabolism and regulate blood sugar.

10. Improved Sleep Patterns

There's some evidence that NAD+ levels influence circadian rhythms and sleep patterns. By boosting NAD+ through NR supplementation, it might help regulate sleep, particularly in individuals who suffer from age-related sleep disturbances.

Absorption and Bioavailability: NR vs. NMN

Nicotinamide Riboside (NR)

• Absorption: NR is readily absorbed when taken orally and can cross cell membranes easily. Once in the body, NR is converted into NAD+ through a two-step process involving conversion into nicotinamide mononucleotide (NMN) first, then into NAD+. Research suggests that NR has good bioavailability and is efficiently converted into NAD+ in various tissues, including the liver, muscle, and brain.

• Bioavailability: Studies indicate that NR is well absorbed in humans and animals, with some data suggesting it might be absorbed more efficiently than NMN in certain forms (like in capsules or liquid form). NR can be taken without the need for any special transporters, making it easy for the body to use.

Nicotinamide Mononucleotide (NMN)

• Absorption: NMN needs to be converted into NR in the gut before it can be utilized by the body. This initial step could potentially limit its efficiency compared to NR. However, more recent studies have shown that NMN may also be absorbed directly into cells, particularly via special transporters (like SLC12A8), and enter the bloodstream more effectively than previously thought.

• Bioavailability: While NMN also raises NAD+ levels in the body, its absorption has historically been considered less efficient than NR's because of the need for conversion. However, advancements in NMN formulations (like enteric coatings) are aimed at improving its stability and absorption rate.

Which Has Better Absorption?

The answer depends on various factors, including the form of the supplement and individual differences in absorption. However, NR tends to be better absorbed and more bioavailable in its unaltered form when compared to NMN, which must undergo conversion in the body before becoming useful. Some of the advantages NR has in terms of absorption include:

• Direct absorption into the bloodstream without the need for conversion in the digestive tract.

• Faster conversion into NAD+ since it doesn't require as many metabolic steps as NMN.

That said, NMN has been shown to be quite effective as well, and recent studies have shown promising results in terms of direct absorption, though the evidence is still developing.

Which One Is Better for You?

Both NR and NMN raise NAD+ levels and may offer similar health benefits, such as supporting energy production, metabolic function, and healthy aging. The primary difference lies in their absorption and bioavailability, where NR is often considered to have a slight advantage in terms of how easily it's absorbed and converted into NAD+. However, as with any supplement, the effectiveness can vary depending on individual responses, and it's always a good idea to consult a healthcare provider to determine which supplement might be more suitable for your needs.

In summary:

• NR is generally considered better absorbed and more efficient in raising NAD+ levels due to its simpler conversion process.

• NMN may have slightly more complex absorption and conversion steps, but it's still effective, especially with newer formulations designed for better bioavailability.

 The Health claims above may not be scientifically proven as yet, as they may not have been updated on the "Health Claims Register".
Although they have been shown in latest study research to "May Help” the following -