Vitamin B3 Nicotinamide Capsules 

High Strength B3 NON Flush Capsules 500mg

Health Benefits of B3 Nicotinamide

🧬 WHAT IT IS

Nicotinamide (niacinamide) is the amide form of vitamin B3 (niacin) — an essential water-soluble vitamin found in foods like meat, fish, nuts, and grains.
Unlike niacin (nicotinic acid), nicotinamide does not cause flushing and has different pharmacological properties.

✅ EVIDENCE-SUPPORTED HEALTH BENEFITS (at ~500 mg/day)

1. Supports Cellular Energy and NAD⁺ Production

• Nicotinamide is a direct precursor for NAD⁺ (nicotinamide adenine dinucleotide), a molecule required for energy metabolism in all cells.

• NAD⁺ fuels mitochondrial ATP production, DNA repair, and antioxidant defense.

• Clinical relevance: helps maintain healthy cellular energy and resilience — particularly in tissues with high turnover (skin, brain, immune cells).

• Source: Imai S, Guarente L. Cell Metab. 2014;19(4):570-82.

2. Skin & DNA Repair Benefits

• Oral nicotinamide 500 mg twice daily has been shown in human trials to reduce rates of new non-melanoma skin Condition  (basal and squamous cell carcinoma) in high-risk individuals.

• Study: Chen AC et al., New England Journal of Medicine 2015 — 386 participants, 12 months.

  • 23% reduction in new skin "c" vs placebo.

  • Safe and well tolerated.

• Mechanism: enhances DNA repair after UV damage and improves skin barrier/immune surveillance.

3. Neuroprotective Effects (Brain & Nerve Health)

• Nicotinamide supports NAD⁺-dependent neuronal repair and mitochondrial protection.

• Animal and early human data suggest benefit in neurodegenerative conditions (e.g., Alzheimer’s, Parkinson’s, glaucoma, peripheral neuropathy).

• Clinical pilot trials show improved cognitive resilience and reduced neuroinflammation markers, though larger RCTs are ongoing.

• Sources:

  • Kaneko S. Front Aging Neurosci. 2021.

  • Green KN et al. J Neurosci. 2008.

4. Metabolic & Anti-Inflammatory Support

• Nicotinamide has mild anti-inflammatory and insulin-sensitising effects.

• At 500–1000 mg/day, studies show modest improvements in glycaemic control, lipid profile, and systemic inflammation (via PARP/NF-κB inhibition).

• Sources: Bedoya FJ et al. Clin Exp Pharmacol Physiol 1996; Revollo JR et al. Mol Cell Biol 2004.

5. Skin Health & Cosmetic Benefits

• Enhances skin barrier function, increases ceramide production, reduces redness and hyperpigmentation, and supports even tone.

• Oral use supports overall skin health and hydration, complementing topical niacinamide serums.

• Sources: Bissett DL et al. Dermatol Surg 2005; Draelos ZD et al. Cutis 2013.

6. Adjunct in Pellagra Prevention

• Classic role: prevents or corrects vitamin B3 deficiency (pellagra), which causes dermatitis, diarrhea, and dementia.

• 500 mg/day more than covers daily requirement (RDA ≈ 14–16 mg), used therapeutically not nutritionally.

⚠️ SAFETY & DOSAGE NOTES

🧠 PRACTICAL USE CASES FOR 500 mg NICOTINAMIDE CAPSULES

The Health claims below may not be scientifically proven as yet, as they may not have been updated on the "Health Claims Register".

Although they have been shown in latest study research to "May Help” the following -