📅 Last updated: July 2026 · 🇬🇧 UK supplement supplier since 2016
⚠️ Novel Food Notice — Trans-Resveratrol
Trans-resveratrol in supplement form is currently a novel food ingredient under review in the UK under retained EU Novel Food Regulation (EU) 2015/2283. This product is sold as a food supplement for adults 18+ only. Not a medicine. Not intended to diagnose, treat, cure or prevent any disease. Consult your GP before use if on prescription medication, particularly blood thinners (warfarin) — resveratrol may have anticoagulant interactions at higher doses.
✅ Food Supplement: NR + Trans-Resveratrol 500mg Capsules are food supplements — not medicines. Not intended to diagnose, treat, cure or prevent any disease. No authorised EU/UK health claims exist for NR (Nicotinamide Riboside) or trans-Resveratrol. All content is educational background and factual specification only. Food supplement — not a medicine.
⚠️ Consult Your GP Before Use If: You are on any prescription medication · on blood thinners (warfarin, heparin, aspirin) — resveratrol may potentiate anticoagulant effects · have a hormone-sensitive condition — resveratrol has weak oestrogenic activity · are pregnant or breastfeeding · have a diagnosed medical condition · are under 18. Food supplement — not a medicine.
🔍 Quick Answer — What Is This Product?
NR + Trans-Resveratrol 500mg Capsules UK from Charge Products (Big Idea Services Ltd, Co. No. 11645389) — 250mg Nicotinamide Riboside (NR) + 250mg trans-Resveratrol (grape-derived) = 500mg total active per capsule. Vegan HPMC shell. Zero fillers. In-house encapsulated at our 5 Star FSA rated Essex facility. 160,000+ verified marketplace sales since 2016. Same-day UK dispatch before 3:30pm. Food supplement — not a medicine. No authorised EU/UK health claims for NR or trans-resveratrol. Trans-resveratrol is a novel food ingredient under UK review.
⚡ Key Features at a Glance
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🧬 NR + Trans-Resveratrol 500mg Capsules UK — The NAD+ Longevity Stack
Buy NR + Trans-Resveratrol 500mg capsules UK direct from Charge Products — an established UK in-house supplement manufacturer since 2016. Each capsule provides 250mg Nicotinamide Riboside (NR) and 250mg trans-Resveratrol (grape-derived) — 500mg total active — in a vegan HPMC shell with zero fillers and no excipients of any kind.
NR and trans-Resveratrol are the combination most associated with NAD+ longevity research — popularised by Professor David Sinclair at Harvard Medical School and studied extensively in the context of sirtuin activation and cellular NAD+ metabolism. NR raises NAD+ levels as a vitamin B3-derived precursor via the Preiss-Handler pathway (Christen et al., 2025, Nature Metabolism). Trans-resveratrol is a stilbene polyphenol found in grape skin that activates SIRT1 — a NAD+-dependent deacetylase enzyme. Educational context — not a health claim. Food supplement — not a medicine.
160,000+ verified marketplace sales since 2016 · Big Idea Services Ltd, Co. No. 11645389 · 5 Star FSA Food Hygiene Rating · Same-day UK dispatch before 3:30pm. Food supplement — not a medicine.
🔬 Why NR and Trans-Resveratrol — The Research Background
🧬 NR + RESVERATROL — HOW THEY INTERACT
NR → NAD+ Role
Nicotinamide Riboside (NR) → converts to NAD+ via the Preiss-Handler pathway → raises circulating and cellular NAD+ levels → provides substrate for NAD+-consuming enzymes including sirtuins
Trans-Resveratrol Role
trans-Resveratrol → activates SIRT1 (Sirtuin 1) → SIRT1 is a NAD+-dependent deacetylase · requires NAD+ to function · resveratrol increases SIRT1 activity · NAD+ provided by NR is the fuel SIRT1 uses
The combination rationale: NR provides the NAD+ substrate · resveratrol activates the enzyme that consumes it. This is a mechanistic hypothesis based on published biochemistry. No combined human RCT has directly confirmed this as a superior approach to either compound alone. Educational context — food supplement, not a medicine. Christen et al. 2025, Nature Metabolism →
⚖️ NR vs NMN — What Is the Difference?
| Factor | NR (This Product) | NMN |
|---|---|---|
| Full name | Nicotinamide Riboside | Nicotinamide Mononucleotide |
| CAS number | 1341-23-7 | 1094-61-7 |
| NAD+ pathway | Preiss-Handler (via conversion to NA) | Preiss-Handler (via conversion to NA) |
| Biosynthetic step | One step earlier than NMN | One step closer to NAD+ than NR |
| NAD+ effect (Christen 2025) | ✅ Sustainably doubles circulating NAD+ | ✅ Sustainably doubles circulating NAD+ |
| Classic longevity pairing | ✅ NR + Resveratrol (this product) | NMN + Resveratrol (separate product) |
| Available from Charge Products | ✅ This product · also standalone NR capsules | ✅ NMN 500mg · 700mg · powder · combinations |
🍇 What Is Trans-Resveratrol?
Trans-resveratrol (CAS 501-36-0) is the biologically active stereoisomer of resveratrol — a stilbene polyphenol found naturally in grape skin, red wine, Japanese knotweed (Polygonum cuspidatum) and peanuts. The trans- form is the active isomer — cis-resveratrol has significantly lower biological activity. Our capsules use trans-Resveratrol derived from grape.
⚠️ Trans-Resveratrol — UK Novel Food Status
Trans-resveratrol in supplement form is under novel food review in the UK under retained EU Novel Food Regulation (EU) 2015/2283. It is sold legally as a food supplement in the UK with appropriate compliance notices. This product is sold for adults 18+ only. Not for use during pregnancy or breastfeeding. Consult your GP before use if on prescription medication — particularly anticoagulants, as resveratrol may potentiate their effects. No authorised EU/UK health claims exist for trans-resveratrol. Food supplement — not a medicine.
🧪 Full Product Specification
| Ingredient 1 | Nicotinamide Riboside (NR) · CAS 1341-23-7 · 250mg per capsule ✅ |
| Ingredient 2 | trans-Resveratrol (grape-derived) · CAS 501-36-0 · 250mg per capsule ✅ |
| Total active per capsule | 500mg (250mg NR + 250mg trans-Resveratrol) ✅ |
| Resveratrol form | trans-Resveratrol (active stereoisomer) — not cis-resveratrol |
| Resveratrol source | Grape-derived |
| Novel food status | ⚠️ Trans-resveratrol under novel food review in UK — sold as food supplement with compliance notice |
| Capsule shell | HPMC — vegan, plant-derived ✅ |
| Fillers / excipients | NONE ✅ |
| Allergens | Free from: soy · gluten · dairy · egg · nuts |
| Suitable for | Vegans · Vegetarians · Adults 18+ |
| Encapsulation | In-house · own UK facility · 5 Star FSA rated ✅ |
| Authorised health claims | None — no authorised EU/UK claims for NR or trans-resveratrol · Educational context only |
| Seller | Big Idea Services Ltd · Co. No. 11645389 · Est. 2016 |
| UK dispatch | 🇬🇧 Same-day before 3:30pm Mon–Fri ✅ |
💡 How to Use & Store
Suggested use: 1 capsule per day with food. Morning with breakfast preferred — resveratrol absorption is enhanced with a fat-containing meal. Take consistently daily.
Duration: Give it a minimum of 8–12 weeks — consistent with published NAD+ precursor trial durations.
Blood thinners: Resveratrol may potentiate anticoagulant effects. Consult your GP before use if on warfarin, heparin, aspirin or any anticoagulant medication.
Storage: Below 25°C, away from direct sunlight and moisture. Keep sealed when not in use. Food supplement — not a medicine.
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Full range
❓ Frequently Asked Questions
What is in each NR + Trans-Resveratrol capsule?
250mg Nicotinamide Riboside (NR, CAS 1341-23-7) + 250mg trans-Resveratrol (grape-derived, CAS 501-36-0) = 500mg total active. Vegan HPMC shell. Zero fillers. Food supplement — not a medicine.
Why combine NR and trans-resveratrol?
NR converts to NAD+ which provides substrate for SIRT1. Trans-resveratrol activates SIRT1 — a NAD+-dependent deacetylase enzyme. The combination is most associated with Professor David Sinclair's longevity research at Harvard. The rationale: NR provides the NAD+ fuel, resveratrol activates the sirtuin enzyme that uses it. Mechanistic hypothesis — food supplement, not a medicine. No authorised EU/UK health claims for NR or trans-resveratrol.
What is the difference between NR and NMN?
Both are vitamin B3 derivatives that act as NAD+ precursors via the Preiss-Handler pathway. NR is one biosynthetic step earlier than NMN. A 2025 Nature Metabolism trial (Christen et al.) found both sustainably double circulating NAD+. Both are available from Charge Products — NR in this product, NMN in our 500mg, 700mg and powder range. Food supplement — not a medicine.
Is trans-resveratrol a novel food in the UK?
Trans-resveratrol in supplement form is under novel food review in the UK. This product is sold legally as a food supplement with the required novel food advisory. Adults 18+ only. Consult your GP before use. Food supplement — not a medicine.
Can I take this with blood thinners?
Consult your GP first. Resveratrol may potentiate the effects of anticoagulant medications including warfarin, heparin and aspirin. Do not take without GP guidance if on any anticoagulant or blood-thinning medication. Food supplement — not a medicine.
Is this product vegan?
Yes — HPMC (hydroxypropyl methylcellulose) vegan capsule shell. No gelatin. No animal-derived ingredients. Suitable for vegans and vegetarians. Food supplement — not a medicine.
When should I take NR + Trans-Resveratrol?
Morning with breakfast. Resveratrol is fat-soluble and absorption is enhanced with a meal containing fat. Consistent daily use for at least 8–12 weeks. Food supplement — not a medicine.
Where can I buy NR and trans-resveratrol capsules UK?
Buy NR + Trans-Resveratrol 500mg capsules UK direct from Charge Products (Big Idea Services Ltd, Co. No. 11645389) on this page or via our eBay listing →. 160,000+ verified sales. 5 Star FSA. Same-day dispatch. Food supplement — not a medicine.
🛒 ALSO AVAILABLE ON EBAY UK
NR + Trans-Resveratrol 500mg Capsules · No Fillers · Vegan HPMC
160,000+ verified sales · UK in-house since 2016 · same-day dispatch
View on eBay →⭐ What Our Customers Say
"We have tested a few brands of NMN and Resveratrol and the performance of the products from Charge consistently out perform the others."
KP · GB · ✅ Verified
"I've been buying from Charge for about 7 or 8 years by now — everything I've bought is high quality with prompt delivery."
Carole · GB · ✅ Verified
"Great product. Consistently high quality and prompt delivery every time."
Verified UK customer · ✅ Verified
Read all reviews on Trustpilot →
📚 Research References — Educational Context Only
- Christen et al. (2025, Nature Metabolism) — doi:10.1038/s42255-025-01421-8 — NR and NMN raise NAD+ via Preiss-Handler pathway · educational context only
- Yoshino et al. (2021, Science) — PubMed 33888596 — NMN in postmenopausal women · educational context only
- Howitz et al. (2003, Nature) — PubMed 14574228 — resveratrol activates SIRT1 · educational context only
- Sinclair DA, Guarente L (2006, Scientific American) — resveratrol and sirtuin biology · educational context only
Educational context only — not health claims. No authorised EU/UK health claims for NR or trans-resveratrol. Food supplement — not a medicine.
🏭 WHY BUY FROM CHARGE PRODUCTS
Big Idea Services Ltd · Co. No. 11645389 · Est. 2016 · 5 Star FSA · 160,000+ Verified Sales
✅ In-House Since 2016
Own UK facility · not contract manufactured · full chain of custody
✅ 5 Star FSA Food Hygiene
Southend-on-Sea City Council · verifiable at ratings.food.gov.uk
✅ 160,000+ Verified Sales
Publicly verifiable · eBay: charge-products-uk · since 2016
✅ Same-Day UK Dispatch
Before 3:30pm Mon–Fri · free delivery over £10
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Disclaimer: NR + Trans-Resveratrol 500mg Capsules are food supplements — not licensed medicines. Not intended to diagnose, treat, cure or prevent any disease or medical condition. No authorised EU/UK health claims exist for NR (Nicotinamide Riboside, CAS 1341-23-7) or trans-Resveratrol (CAS 501-36-0) as food supplement ingredients. Trans-resveratrol is a novel food ingredient under review in the UK — sold legally as a food supplement with appropriate compliance notices. Consult your GP before use if on anticoagulant or blood-thinning medications, if you have a hormone-sensitive condition, if pregnant, breastfeeding, or under 18. All content is educational background only — not health claims. Sold by Big Idea Services Ltd, Company No. 11645389, Unit 1, 8 Towerfield Road, Towerfield Industrial Estate, Southend-on-Sea, Essex SS3 9QE. Food supplement — not a medicine.
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